Klinefelter sendromu ilk tan›mlanan kromozom anomalisi olup temel olarak hipergonadotropik hipogonadizm ve önükoid vücut yap›s› ile karakterizedir. S›kl› ¤›. ‘de tarif edilen Klinefelter sendromu hipogonadiz ve infertilitenin en sık tek nedenidir. Paternal mayoz hataları Klinefelter sendromunun yarısını oluştururken . Key words: Antisocial personality disorder, Klinefelter’s syndrome. ÖZET. Antisosyal kişilik bozukluğu ile karşımıza çıkan 18 yaşında Klinefelter’s sendromu tanısı.
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Although rare cases of spontaneous fertilization are published in the literature, spontaneous fertilization is not possible in patients with Klinefelter syndrome. Also, the length of the lower extremities seen in prepubertal period is more dominant and it is thought to be the result of a chromosomal aberration In Klinefelter syndrome, the most typical clinical manifestation is testicles not getting bigger despite the klinefelfer of secondary sex characteristics.
Serum testosterone level often rises up to the lower levels of normal range.
Klinefelter Sendromu: klinefelter syndrome. – Free Online Library
In a study using DNA probes, cases of paternal division errors constitute Rec Prog Horm Res ; More rarely occur genitourinary malformations, such as hypospadias and undescended testes 10, Marketing Sales-Project Klinefelger Phone: It should be noted that patients without the typical features might have Klinefelter syndrome as well.
A serum FSH level higher than normal range with very low levels of testosterone is an important sign for Klinefelter syndrome. Normal levels can be seen in patients with mosaic form, while much lower levels is seen in patients with high-chromosomal defects. The characteristics of patients suspected of Klinefelter sedromu varies according to age groups.
Klinefelter Sendromu: klinefelter syndrome.
It has been shown that in these patients, some tissues have 47,XXX and some others have 46,XY chromosomes. Orphanet J Rare Dis ;1: Testicular dysgenesis affecting the seminiferous tubules principally, with chromatin-positive nuclei. It was thought to be an endocrine disease yet the etiology was not found at that time.
Studies focused on the maternal period, those examining various factors such as the maternal age, did not reveal any related factor increasing the probability for Klinefelter syndrome To use the web pages with http: Subscription and Public Relations Department Phone: In mosaic forms, clinical features vary widely.
Unlike the classic presentation of long arms and long legs, the lower extremity is disproportionately longer, in comparison to the upper extremity.
A Newborn with Klinefelter and Trisomy 18 Syndrome: Case Report | Article | Türkiye Klinikleri
Dandona P, Rosenberg MT. Intramuscular injections of testosterone enanthate or testosterone cypionate are the most commonly used testosterone replacement therapy agents.
Also preparations applied to the skin in a patch or gel form have been developed. The ejaculate of patients with mosaic form is more likely to contain sperm.
However, an amniocentesis on suspicion of Klinefelter is not within the perinatal routine because it does not show any significant features in ultrasound examination during klinegelter. The majority of patients are diagnosed with Klinefelter syndrome during their puberty period. In addition, in these patients, free testosterone levels are generally lower due to increased sex hormone binding globulin.