Novartis’ Galvus (vildagliptin) is a member of a new class of oral antidiabetic agents known as dipeptidyl peptidase IV inhibitors (DPP-IV) inhibitors or ‘incretin . Galvus Approval Status. FDA Approved: No Brand name: Galvus Generic name: vildagliptin. Previous Name: LAF Company: Novartis Pharmaceuticals. Vildagliptin is an oral anti-hyperglycemic agent (anti-diabetic drug) of the dipeptidyl The European Medicines Agency has also approved a combination of vildagliptin and metformin, vildagliptin/metformin (Eucreas by Novartis) as an oral.

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As a potent and selective inhibitor of DPP-4, vildagliptin causes rapid and complete inhibition of DPP-4 activity, resulting in increased fasting and postprandial endogenous levels of the incretin hormones GLP-1 glucagon-like peptide 1 and GIP glucose-dependent insulinotropic polypeptide.

Vildagliptin – Wikipedia

Insulin Aspart Vildagliptin may increase the hypoglycemic activities of Insulin Aspart. The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Asenapine. The therapeutic efficacy novrtis Vildagliptin can be decreased when used in combination with Fluprednidene. Glycodiazine The therapeutic efficacy of Vildagliptin can be increased when used in combination with Glycodiazine.

Icandra (previously Vildagliptin / metformin hydrochloride Novartis)

Fosamprenavir The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Fosamprenavir. Fish oil The novattis or severity of hypoglycemia can be increased when Fish oil is combined with Vildagliptin.

The risk or severity of hypoglycemia can be increased when Amlodipine is combined with Vildagliptin. How useful was this page?

More than 5, male and more than 4, female patients received vildagliptin 50 mg once daily or mg daily. The risk or severity of hypoglycemia can be increased when Darodipine is combined with Vildagliptin.

Oral anti-diabetic drugsinsulins and insulin analogsand other drugs used in diabetes A Troglitazone The risk or severity of hypoglycemia can be increased when Troglitazone is combined with Vildagliptin. Skin disorders Skin lesions, including blistering and ulceration have been reported in extremities of monkeys in non-clinical toxicology studies see section 5. Symptoms Information on the likely symptoms of overdose was taken from a rising dose tolerability study in healthy subjects given Galvus for 10 days.

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The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Ceritinib. The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Norethisterone.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Opipramol Opipramol may decrease the hypoglycemic activities of Vildagliptin.

Vildagliptin launched by Novartis for dual therapy in type 2 diabetes

Linagliptin The risk or severity of angioedema can be increased when Vildagliptin is combined with Linagliptin. The risk or severity of hypoglycemia can be increased when Zimelidine is combined with Vildagliptin.

Bromocriptine The risk or severity of hypoglycemia can be increased when Bromocriptine is combined with Vildagliptin. To view the changes to a medicine you must sign up and log in. By clicking Subscribe, I agree to the Drugs. Desvenlafaxine The risk or severity of hypoglycemia can be increased when Desvenlafaxine is combined with Vildagliptin. Haloperidol The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Haloperidol. It is currently in clinical trials in the U.

The therapeutic efficacy of Vildagliptin can be increased when used in combination with Sulfametopyrazine. The risk or severity of hypoglycemia can be increased when Carboxyamidotriazole is combined with Vildagliptin. After novaftis year mean reductions in HbA 1c were Citalopram The risk or severity of hypoglycemia can be increased when Citalopram is combined with Vildagliptin.

These changes are, however, not considered to be clinically relevant. Gabapentin The risk or severity of hypoglycemia can be increased when Gabapentin is combined with Vildagliptin. Sulfadiazine The therapeutic efficacy of Vildagliptin can be increased when used in combination with Sulfadiazine.

Lamotrigine The risk or severity of hypoglycemia can be increased when Lamotrigine is combined with Vildagliptin.

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Galvus (vildagliptin) FDA Approval Status –

Alteplase The risk or severity of angioedema can be increased when Alteplase is combined with Vildagliptin. Darodipine The risk or severity of hypoglycemia can be increased when Darodipine is combined with Vildagliptin. Icatibant The risk or severity of angioedema can be increased when Vildagliptin is combined with Icatibant.

The risk or severity of angioedema can be increased when Streptokinase is combined with Vildagliptin. The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Quinethazone. In these studies, vildagliptin was administered to more than 9, patients at daily doses of 50 mg once daily, 50 mg twice daily or mg once daily.

No increases in tumour incidence attributable to vildagliptin were observed. Dosulepin Dosulepin may decrease the hypoglycemic activities of Galvhs. Fendiline The risk or severity of hypoglycemia can be increased when Fendiline is combined with Vildagliptin.

Use of vildagliptin has been associated with a risk of developing acute pancreatitis. You will be re-directed back to this page where you will have the ability to comment. The therapeutic efficacy of Vildagliptin can be increased when used in combination with Succinylsulfathiazole.

Noavrtis The therapeutic efficacy of Vildagliptin can be decreased when used in combination with Sirolimus. The risk or severity of hypoglycemia can be increased when Vildagliptin is combined with Rivoglitazone. Rivoglitazone The risk or severity of hypoglycemia can be increased when Vildagliptin is combined with Rivoglitazone. Patients gaalvus vildagliptin in combination with a sulphonylurea may be at risk for hypoglycaemia. Ciglitazone The risk or severity of hypoglycemia can be increased when Vildagliptin is combined with Ciglitazone.

The risk or severity of hypoglycemia can be increased when Nimodipine is combined with Vildagliptin.